What is autoimmune disease?

With Autoimmune issues on the rise today, people are more and more concerned with prevention and how to protect themselves.

What is an Autoimmune condition?

Whenever the body starts attacking its own tissue and cells, we characterize this as autoimmune. Some of the most common autoimmune conditions are hypothyroidism, gastro-intestinal issues, arthritis and many more. Autoimmune conditions are categorized by the organ they attack and are not currently being treated as an attack on the whole immune system.

Here are a small sample list of autoimmune diseases:

  • Rheumatoid Arthritis
  • Sjogren’s arthritis
  •  Lupus
  • Celiac Disease
  • Polymyalgia Rheumatica
  • Multiple Sclerosis
  • Ankylosing Spondylitis
  • Vasculitis
  • Inflammatory Bowel Disease, Crohn’s, Ulcerative Colitis
  • Type 1 Diabetes

What causes Autoimmune conditions?

As a growing number of conditions falls under the autoimmune category, we wonder the possible causes. Some are more likely to have auto-immunity in their families, some from toxins, more from poor diet (weight can play a factor), smoking, drug use (including prescription), severe or chronic stress and hormonal imbalances. There are more than 80 classified autoimmune diseases and they can be difficult to determine where they come from and which one you have.

What are the most common symptoms of Autoimmune disease?

  • Fatigue
  • Joint Pain
  • Swelling
  • Skin problems (like eczema)
  • Abdominal pain and discomfort
  • Recurring Fevers
  • Swollen Glands

If these symptoms sound vague and like the symptoms of a lot of different diseases, you would be right and this makes diagnosis so difficult.

What testing is done?

Doctor’s start with laboratory testing to determine which type or category of disease a patient has and may order the following tests:

  • Antinuclear Antibodies (ANA)
  • Autoantibodies (thyroid or other organ based)
  • Immunoglobulin A (IgA)
  • C-reactive Protein (CRP) Test
  • Erythrocyte Sedimentation Rate (ESR)
  • Complement Test C1, C1q, C2, C3, C4, CH50, CH100, Total Complement

How is it treated?

Autoimmune conditions are treated in several ways such as diet, exercise, nutraceuticals, hormones, anti-inflammatories and sometimes steroids if the attack is severe enough. Most people try and use natural alternatives and only steroids when more severe attacks occur. Below is a list of treatments including Dr. Walker’s favorite functional medicine strategies:

  • Diet: Autoimmune Protocol Diet (AIP) similar to paleo but much stricter (see a basic list on our website link)
  • Exercise: Low impact exercise such as yoga, biking, swimming and walking with mild weight lifting being done as ability allows
  • Nutraceuticals: Vitamin A and D, Liposomal Glutathione, Short-chain Fatty acids, Turmeric, Boswellia, L-Glutamine, essential minerals (some of Dr. Walker’s list)
  • Steroids and autoimmune suppressants: in more severe cases: Hormones, estrogen, progesterone, thyroid hormone, melatonin to help balance the system.
  • Anti-inflammatory drugs: Ibuprofen and Naproxen

If you are struggling with what you think may be autoimmune don’t suffer alone, there are lots of health care professionals to help you and at our office we work together with your specialist to make sure you are uniting both functional medicine and Western care to have the best and healthiest you possible. We don’t want the feeling of sickness to prevent you from enjoying life!

Is it a Food Sensitivity or Food Allergy?

What are delayed-onset reactions?

When a separate non-anaphylactic reaction occurs within 2-72 hours after exposure, it is considered a delayed-onset reaction.  Most people believe that these are due to foods. However since allergies are cumulative it may also be from environment allergens as well as insect reactions. This reaction is mediated by the IgG antibody and can cause a variety of symptoms, not just the common ones seen in seasonal allergies or anaphylaxis.

What are the most common foods associated in delayed-onset reactions

  • Cow’s milk
  • Wheat gluten (gliadin)
  • Gluten (in wheat, oats, rye and barley)
  • Yeast
  • Egg whites
  • Cashews
  • Egg yolks
  • Garlic
  • Soy beans
  • Brazil nuts
  • Almonds
  • Corn
  • Hazelnuts
  • Pineapple
  • Sesame seeds
  • Kale
  • Navy beans

What are the IgG and IgE antibodies?

Immunoglobulin, also know as an antibody, resides in the blood, which is why the most thorough testing for food allergies is done with a blood test.  Antibodies are the body’s natural defense against fungus, viruses, bacteria, cancer cells and allergens. They bind to these substances so that the body can detect and kill them.  The major types of antibodies are: IgA, IgM, IgE, IgG and IgD. But for the purpose of allergies we will just address IgE and IgG.

IgG antibodies are found in most body fluids and are the smallest and most abundant immunoglobulin. They fight bacterial and viral infections as well as allergens. They are the only type of antibody able to cross the placenta in pregnant women to help protect the baby.

IgE antibodies are found in the lungs, skin, and mucus membranes. They react to foreign substances such as pollen, fungus, medications, poisons, animal dander, and food items. Patients with allergies and children with anaphylactic reactions will have high levels of IgE antibodies.

What are the symptoms of delayed-onset reactions?

  • Sore throat
  • Decreased ability to concentrate
  • Achy joints
  • Skin conditions (eczema, rash, hives)
  • Trouble sleeping
  • Gas, bloating
  • Constipation or diarrhea
  • Headaches
  • Trouble sleeping
  • Aggressive or hyperactive behavior in children
  • Colic and increased spit up
  • Mental fogginess

Since delayed-onset reactions are less severe than anaphylactic allergies what happens if I ignore them?

When inflammation is present in the body and is left untreated the immune system is in a state of constant hyperactivity making the body feel as if it is working in over- drive. An over-worked immune system may be more susceptible to the many autoimmune disease reactions and inflammatory conditions we see today. Whether this is the complete cause or whether this simply makes it worse is unknown.

Autoimmune diseases that have been linked to a hyperactive immune system include the following:

  • Thyroid disease
  • Infertility
  • Chronic fatigue
  • Adrenal disease

Inflammatory diseases that are made worse by constant inflammation in the body include some of the following:

  • Fibromyalgia
  • Crohn’s
  • Ulcerative colitis
  • Eczema
  • Psoriasis
  • Arthritis (Rheumatoid and Osteoarthritis)
  • Gout 

What do delayed-onset reactions look like in children? 

In children, food sensitivities can often be interpreted as poor behavior.  Children who consistently don’t feel well and are over-tired tend to act out in many ways.  Some of the conditions that have improved by testing and removing sensitivities include, but are not limited to, the following:

  • Poor sleep
  • ADD/ADHD
  • Autism Spectrum Disorders
  • Aggressive behavior
  • Headaches
  • Tummy aches and colic
  • Trouble concentrating
  • Poor immune system
  • Sensory disorders
  • Ear infections (due to improper drainage)

Can I self-test?

Self-testing is possible, but certainly not easy, which is why most patients will opt for blood testing. The following self-test requires strict adherence to the process with absolutely no cheating which most people find almost impossible.

How to self-test:

For 30 days eliminate all foods found in the above list of common foods associated with delayed-onset reactions. Keep a detailed journal of how you feel during the time these foods have been eliminated.

After 30 days, start adding in one food at a time. Re-introduce only this food for about 3 days. If you do not experience symptoms on the first day of the test then double the quantity on the second day. If no reaction occurs then you can move to the next food. If you do have a reaction to the food, put it on your list of foods to avoid. Remember to keep journaling.

Repeat this process for each new food item until you developed a list of foods you can eat and foods to avoid.

For more specific instructions, ask our office to provide you with a specific elimination diet.  It can also be nice to do a Medi-clear cleanse at the same time to detox your body of inflammation and also mildly cleanse your liver.

How does the blood testing work and what do the results tell me?

When doing blood testing for food allergies we require that you are not currently suffering from seasonal allergies or have recently had a cold or flu. If you have taken any antihistamines 24 hours prior to the test, you may have false readings.  We generally don’t test children under four, but there are some exceptions.  For severe cases in children younger than four there is a heel stick test or we test mom and treat the child according to the positive results on mom’s test.  This is not a fasting blood test.

Our blood panel tests 190 food allergens including most foods as well as spices, yeast and sugars. The results are then carefully examined by one of our doctors to determine the most effective plan for treatment. This will included a recommended diet and the best approach to dealing with your specific allergens.

At In Health Clinic we are always available to discuss your health concerns and would be happy to help you decide whether or not this test is right for you.

Previously we wrote Allergies Part I, which was an extensive overview of what allergies are and how they can seriously affect health.  For a review of this article look at our website under medical resources.  (https://in-healthclinic.com/allergies-part-i/)

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